BCAA 5000 utilizes the research-validated 2:1:1 ratio (leucine:isoleucine:valine), proven to effectively and efficiently promote muscle growth and recovery and reduce training-related soreness What's more, research had shown that only 2–3 grams of leucine is needed to maximize muscle protein synthesis. The point—don't pay more for the extra BCAAs you don't need, especially when science shows consuming too much BCAAs can negatively affect blood lipid profiles.